VERASTEM, INC.
NEEDHAM, MA

We are a clinical-stage biopharmaceutical company focused on developing therapies to improve the lives of patients diagnosed with cancer in ways that are truly meaningful to them. With deep expertise, agility and purpose, we are identifying and advancing late-stage, first-in-class clinical assets to market. We are concentrating on a portfolio of small molecule drugs inhibiting critical signaling pathways in cancer, including the phosphoinositide 3-kinase (PI3K) and focal adhesion kinase (FAK) pathways. These signaling pathways are abnormal in cancer and promote tumor survival. Preclinical research has shown these pathways also contribute to the protective nature of the tumor microenvironment, thereby limiting the effectiveness of existing cancer treatments. Our lead clinical product candidate targeting the FAK pathway is defactinib. Defactinib is currently being evaluated in three separate clinical collaborations in combination with immunotherapeutic agents for the treatment of several different cancer types, including pancreatic, ovarian and non-small cell lung cancer (NSCLC) and mesothelioma. Disclaimer: You are now leaving www.verastem.com and are going to a website that is not operated by Verastem. We are not responsible for the content or availability of linked sites. Verastem offers links to other third party websites that may be of interest to our website visitors. The links provided in our website are provided solely for your convenience and may assist you in locating other useful information on the Internet. When you click on these links you will leave the Verastem’s website and will be redirected to another site. These sites are not under the control of Verastem. Verastem is not responsible for the content of linked third party websites. We are not an agent for these third parties nor do we endorse or guarantee their products. We make no representation or warranty regarding the accuracy of the information contained in the linked sites. We suggest that you always verify the information obtained from linked websites before acting upon this information. Also, please be aware that the security and privacy policies on these sites may be different than Verastem policies, so please read third party privacy and security policies closely. If you have any questions or concerns about the products and services offered on linked third party websites, please contact the third party directly. Disclaimer: You are now leaving www.verastem.com and are going to a website that is not operated by Verastem. We are not responsible for the content or availability of linked sites. Verastem offers links to other third party websites that may be of interest to our website visitors. The links provided in our website are provided solely for your convenience and may assist you in locating other useful information on the Internet. When you click on these links you will leave the Verastem’s website and will be redirected to another site. These sites are not under the control of Verastem. Verastem is not responsible for the content of linked third party websites. We are not an agent for these third parties nor do we endorse or guarantee their products. We make no representation or warranty regarding the accuracy of the information contained in the linked sites. We suggest that you always verify the information obtained from linked websites before acting upon this information. Also, please be aware that the security and privacy policies on these sites may be different than Verastem policies, so please read third party privacy and security policies closely. If you have any questions or concerns about the products and services offered on linked third party websites, please contact the third party directly. Mr. Paterson has over 25 years of experience in management roles at healthcare and biotechnology companies, including as CBO, COO and CEO, with specific expertise in oncology drug and diagnostic product development, business development and launch planning. Prior to his current role, he served as CBO of Verastem. Mr. Paterson was the Co-founder and COO of On-Q-ity, a developer of technology to capture and analyze circulating tumor cells, and the founding CEO of The DNA Repair Company (merged to form On-Q-ity), which developed oncology-focused molecular diagnostics. Prior to that, Mr. Paterson was Head of Global Strategy for Specialty Market and Patient-Level Data at IMS Health, after playing a key role in the acquisition of PharMetrics by IMS Health as VP, Marketing and Corporate Development. While at PharMetrics, Mr. Paterson led the development of an innovative suite of pharmaceutical product launch tools that became the basis of the company’s product line. Earlier in his career, Mr. Paterson was on the founding management team of CareTools, a healthcare information systems company, OnCare, an oncology physician practice management company with $100 million in annual revenue, and Axion, an oncology pharmaceutical and clinical service firm with an annual revenue of over $250 million when acquired by Bristol Myers Squibb. Prior to his involvement in industry, Mr. Paterson led the clinical operations for a nationwide cancer cooperative group headquartered at the Dana Farber Cancer Institute. Mr. Paterson holds a B.A. in Biology from Boston University, and attended the Northeastern University Graduate Pharmacology program. Mr. Bloom joined Verastem in March 2014 and serves as Chief Strategy Officer. His responsibilities include Corporate and Business Development, Medical Affairs, Patient Advocacy and Corporate Communications. Prior to joining the company, Mr. Bloom was Senior Vice President at Ziopharm Oncology where for 6 years he led business development and the commercial planning initiatives for a late stage oncology asset. Before joining Ziopharm, Mr. Bloom was Vice President for the health informatics company Pharmetrics and was part of the leadership team that sold the company to IMS Health in 2005. After leaving Eli Lilly in 2002, he joined the health technology company Inflexxion and built a commercial infrastructure for the start-up organization. Mr. Bloom spent the first 19 years of his career at Eli Lilly and Company in leadership roles in marketing, sales and corporate affairs.